Peptides are short chains of amino acids that act as building blocks of proteins including collagen, elastin and keratin. Each peptide plays a key role in skin’s texture and strength.

In their natural form,peptides can be unstable, so we opted for highly stabilized lab-engineered peptides in our Pro-Collagen Multi-Peptide Booster. These 'synthetic' peptides can penetrate the upper layers of skin and 'activate' areas that help visibly improve tone, hydration, a feeling of suppleness and a smoother surface. Did you know? Synthetic peptides are created as exact copies of protein fragments in skin. They’re more stable on and within skin, remain intact on skin longer and better reach their target areas.

While the original Peptide Booster was a great formula with wonderful benefits, the Pro-Collagen Multi-Peptide Booster features newer, highly specialized peptides that have a more targeted impact on loss of firmness, decreased resilience, wrinkles and skin's foundational architecture for even better results. Both formulas share a similar lightweight gel texture.

A particularly innovative peptide in this formula,tridecapeptide-1, works by interrupting a key step within skin that leads to the formation of expression lines. With this process sidestepped, facial lines and wrinkles begin to smooth out, and skin looks younger and less fatigued.  

No. This focused formula complements your other anti-aging products by reinforcing and restructuring the surface layers of skin with highly specialized peptides that affect the dermal-epidermal junction. This unique, targeted benefit is something ingredients such as vitamin C, niacinamide and retinol just cannot do; however, each of those ingredients have their own benefits and can be used alongside peptides.

It’s not a problem to use the Pro-Collagen Multi-Peptide Booster if you have sensitive or rosacea-prone skin. In fact, its fragrance-free formula contains potent skin-soothing and skin-replenishing antioxidants that help calm.

When using the Pro-Collagen Multi-Peptide Booster, you will notice smoother expression lines and wrinkles within 15 minutes with results lasting up to 4 hours. After 4 weeks of consistent use, you will notice a reduction of depth and volume in the appearance of fine lines and wrinkles.

You can apply the Pro-Collagen Multi-Peptide Booster up to twice per day. After cleansing, toning and exfoliating, apply the rest of your serums, treatments and boosters in order from thinnest to thickest texture. Finish with moisturizer as your last step for PM and moisturizer with SPF during the daytime

The Pro-Collagen Multi-Peptide Booster includes a blend of distinctive peptides that are not only used at clinically efficacious levels but are combined with key supporting ingredients that revive healthy cellular energy and influence key collagens and other proteins needed to rebuild and preserve youthful skin. Like all Paula’s Choice products, this booster is also free from natural and synthetic fragrance and other irritants, plus it’s packaged stably to preserve ingredient integrity and efficacy. This product takes a top-down signaling approach to restore and maintain skin's structural support system. While some competitor products may contain more peptides in terms of ingredient count, they are likely using levels below the recommended standard (especially if the product's price is below $40).

While Paula's Choice products are fragrance-free, each product may have a unique scent due to its ingredients. The scent of the Pro-Collagen Multi-Peptide Booster is primarily from the ingredient tridecapeptide-1, which dissipates quickly after application. The perception of smell can vary greatly between individuals, so what one person notices, another may not notice at all. Many customers find that they quickly get used to the unique scents of Paula's Choice products and that the benefits outweigh any potential drawbacks. Learn more about fragrance-free skin care. 

Yes, peptides and retinol can complement each other in an anti-aging routine. Retinol helps improve the look of uneven texture by supporting skin’s natural renewal process, while peptides help support firmer-looking skin and can be a good choice for pairing with more sensitizing actives. Apply the Pro-Collagen Multi-Peptide Booster before or after your retinol product or use peptides in the morning and retinol at night.

Yes, peptides and vitamin C can be used together. Vitamin C provides antioxidant support while peptides support firmer looking skin. If your skin is sensitive, introduce new combinations gradually.

They can both be effective, but they work differently. Retinol has decades of research supporting its benefits, though it can be more irritating for some people. Peptides can help support firmer-looking skin with less risk of visible sensitivity, making them a good option for reactive skin or for those who don’t tolerate retinol well. Many people use both in their routine for optimal results.

Yes, the lightweight gel texture absorbs quickly without clogging pores or feeling heavy. Peptides help strengthen the skin barrier and calm reactivity, which can benefit acne-prone skin. This booster is also a good option if you find retinol too irritating.

Yes, our boosters are formulated to complement each other, so you can layer them to customize your routine. You can layer the Pro-Collagen Multi-Peptide Booster with others like the C15 Super Booster, 10% Niacinamide Booster or Hyaluronic Acid Booster. Apply boosters from thinnest to thickest texture and introduce new combinations gradually if your skin is sensitive.